السبت، 4 يناير 2014

Popular Painkillers Linked To Increased Heart Attack Risk

Popular Painkillers Linked To Increased Heart Attack Risk


A new international study finds that popular painkillers or anti-inflammatories knows asNSAIDs can increase the risk of heart attackor stroke by a third, with some having a much stronger effect than others, and size of dose also making a difference. However, experts urge patients worried about the findings not to give up on their NSAID medication and to speak to their doctor about their concerns.

Researchers from Hull York Medical School (HYMS), a joint venture between the Universities of Hull and York and the NHS in the UK and the Institute for Clinical Evaluative Sciences in Canada, systematically reviewed 51 large scale studies of non-steroidal, anti-inflammatory drug (NSAID) conducted in Europe, USA, Canada and Australia. Their findings are published online this week the journal PLoS Medicine.

They found that patients with heart problems who used NSAIDs, including diclofenac and indomethacin, had a significantly higher risk of serious cardiovascular events such as heart attack and stroke compared to patients who did not.

Even in doses available over the counter without a doctor's prescription, diclofenac could raise someone's risk of heart attack or stroke, they said.

However, other common NSAIDs, including naproxen and low doses of ibuprofen do not appear to be linked to an increase in risk.

Lead researcher Dr Patricia McGettigan from HYMS told the press that:

"NSAIDs provide pain relief for millions of patients with chronic inflammatory disorders. The cardiovascular risk is well described but often overlooked. In choosing which one of the many available NSAIDs to use, patients and doctors would benefit from knowledge of the balance between benefit and harm for individual NSAIDs."

Many people use NSAIDs in both over the counter and prescription form for pain relief and for their anti-inflammatory effects to treat conditions such as headache, arthritis, back pain,gout, and the aches and fever of flu.







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